Risk_of_malignancy_index_RMI_for_ovarian_cancer v.1

Risk of Malignancy Index (RMI) for ovarian cancer predicts risk that an adnexal mass is malignant.

Therese Lindberg

therese.lindberg@cambio.se

Cambio CDS

To predict the risk that an adnexal mass is malignant.

Use to predict the risk that an adnexal mass is malignant, the RMI. Formula: RMI = menopausal status x ultrasound score x serum CA-125, U/mL Where menopausal status and ultrasound score are as follows: Ultrasound features: 1 if 0-1 present and 3 if ≥2 present Menopausal status*: 1 if Premenopausal or perimenopausal and 3 if Postmenopausal *Postmenopausal status = >1 year of amenorrhea or age ≥50 years if patient is status post hysterectomy. Interpretation: RMI Risk of malignancy ≤200 Low >200 High* *71% sensitive and 92% specific for ovarian cancer.

1.Jacobs I, Oram D, Fairbanks J, Turner J, Frost C, Grudzinskas JG. A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer. Br J Obstet Gynaecol. 1990 Oct;97(10):922-9. doi: 10.1111/j.1471-0528.1990.tb02448.x. PMID: 2223684.

OBSERVATION.rmi.v0, EVALUATION.rmi_assessment.v0, OBSERVATION.lab_test_serum_ca_125.v0