GELF_criteria v.1

Presence of any systemic or B symptoms

Splenic enlargement with inferior margin below the umbilical line

Cytopenia (granulocyte count < 1.0x10⁹/L and/or platelets < 100x10⁹/L)

Any nodal or extranodal tumor mass >7 cm diameter

Involvement of at least 3 nodal sites, each with diameter >3 cm

Compression syndrome (ureteral, orbital, gastrointestinal)

Pleural or peritoneal serous effusion (irrespective of cell content)

Leukemic phase (>5.0 x10⁹/L circulating malignant cells)

Groupe d'Etude des Lymphomes Folliculaires (GELF) Criteria determines if immediate therapy for follicular lymphoma is required.

Therese Lindbergq

therese.lindberg@cambio.se

@CambioCDS

To determine if immediate therapy for follicular lymphoma is required.

Patients must meet ≥1 criteria to be considered “high” tumor burden; criteria below: - Any nodal or extranodal tumor mass >7 cm diameter - Involvement of at least 3 nodal sites, each with diameter >3 cm - Presence of any systemic or B symptoms - Splenic enlargement with inferior margin below the umbilical line - Compression syndrome (ureteral, orbital, gastrointestinal) - Pleural or peritoneal serous effusion (irrespective of cell content) - Leukemic phase (>5.0 x109/L circulating malignant cells) - Cytopenia (granulocyte count < 1.0 x109/L and/or platelets < 100x109/L)

1. Brice P, Bastion Y, Lepage E, et al. Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires. J Clin Oncol. 1997. 15:1110-7.

EVALUATION.gelf_criteria.v0

CDS App Challenge About us