COVID-GRAM_Critical_Illness_Risk_Score_guideline v.1
COVID-GRAM Critical Illness Risk Score provides a possibility of early identification of patients with novel coronavirus disease 2019 (COVID-19) who may develop critical illness and delivering proper treatment and optimizing the use of resources.
COVID-GRAM Critical Illness Risk Score predicts the risk of critical illness in hospitalized COVID-19 patients.
Use to stratify the risk of critical illness for patients admitted to the hospital for presumed COVID-19 infection. Formula COVID-GRAM Risk Score = (X-ray abnormality x 27.1464) + (Age x 0.6139) + (Hemoptysis x 33.6210) + (Dyspnea x 14.0569) + (Unconsciousness x 34.4617) + (Number of comorbidities x 10.3826) + (Cancer history x 31.2211) + (Neutrophil to lymphocyte ratio x 1.25) + (Lactate dehydrogenase x 0.0534) + (Direct bilirubin x 3.0605), where variables are as follows: Variables and Point (Yes=1, No=0): - X-ray abnormality: Yes or No - Age, years - Hemoptysis: Yes or No - Dyspnea: Yes or No - Unconsciousness: Yes or No - Number of comorbidities (Includes COPD, hypertension, diabetes, coronary heart disease, chronic heart disease, chronic kidney disease, cancer, cerebral vascular disease, Hepatitis B, and immunodeficiency.) - Cancer history: Yes or No - Neutrophil to lymphocyte ratio - Lactate dehydrogenase, U/L - Direct bilirubin, μmol/L
Not to be used for non-hospitalized and ED patients. It cannot be used as a criterion for patient admission or discharge.
1. Liang W, Liang H, Ou L, et al. Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19. JAMA Intern Med. 2020.
OBSERVATION.basic_demographic.v1, OBSERVATION.covid_gram_critical_illness_risk_score.v0, OBSERVATION.lab_test-bilirubin.v1
