ASDAS-CRP v.1

Assessment of Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP). Stratifies severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically CRP. It is calculated using five parameters: back pain(0-10), duration of morning stiffness(0-10), patient global assessment of disease activity(0-10), peripheral pain/swelling(0-10) and CRP (level of C-reactive protein, in mg/dL). The disease is considered to be inactive if the score is <1.3, low if the score is in between 1.3-2.0, high when 2.1-3.5 and very high when activity is strictly above 3.5.

Therese Lindberg

therese.lindberg@cambio.se

Cambio CDS

To record the data of Ankylosing Spondylitis Disease Activity Score with CRP.

Use to record data for ASDAS-CRP. The score is based on five parameters: Back pain, duration of morning stiffness, patient global assessment of disease activity, peripheral pain/swelling and CRP (C-reactive protein). Other than CRP, all values are self-reported by the patient and therefore subjective. All variables, except CRP, should be graded on a scale of 0 (least severe) to 10 (most severe). The score is calculated from: ASDAS-CRP = (0.12 x back pain) + (0.06 x morning stiffness) + (0.11 x patient global assessment of disease activity) + (0.07 x peripheral pain/swelling) + (0.58 x ln(CRP + 1)). The disease is considered to be inactive if the score is <1.3, low if the score is in between 1.3-2.0, high when 2.1-3.5 and very high when activity is strictly above 3.5.

1. Lukas C, Landewé R, Sieper J, et al. Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Ann Rheum Dis. 2009;68(1):18-24.

OBSERVATION.lab_test_c_reactive_protein.v1, EVALUATION.asdas_crp.v0