mSOFA_Score_guideline v.1

Modified Sequential Organ Failure Assessment (mSOFA) Score predicts ICU mortality using mostly clinical variables and fewer labs.

Maryam Razavi

maryam.razavi@cambio.se

Cambio CDS

To determine level of organ dysfunction and mortality risk in ICU patients.

Can be used on all patients admitted to an intensive care unit. mSOFA score formula: Addition of the selected points: Variables and assigned points: Respiratory: Points SpO₂/FiO₂ (see table below for >400 0 estimating FiO₂ from oxygen >315 to ≤400 1 flow/delivery rates) >235 to ≤315 2 >150 to ≤235 3 ≤150 4 Liver: Scleral icterus or jaundice present No 0 Yes 3 Cardiovascular No hypotension 0 MAP <70 mmHg 1 Hypotension DOPamine ≤5 or 2 DOBUTamine (any dose) DOPamine >5, 3 EPINEPHrine ≤0.1, or norEPINEPHrine ≤0.1 DOPamine >15, 4 EPINEPHrine >0.1, or norEPINEPHrine >0.1 CNS GCS 15 0 13-14 1 10-12 2 6-9 3 <6 4 Renal <1.2 0 1.2-1.9 1 Creatinine, mg/dL 2.0-3.4 2 3.5-4.9 3 >5.0 4 Interpretation: mSOFA Score 0-7= 4% 30-day mortality mSOFA Score 8-11= 31% 30-day mortality mSOFA Score >11= 58% 30-day mortality

1. Grissom CK, Brown SM, Kuttler KG, Boltax JP, Jones J, Jephson AR, Orme JF Jr. A modified sequential organ failure assessment score for critical care triage. Disaster Med Public Health Prep. 2010 Dec;4(4):277-84. doi: 10.1001/dmp.2010.40. PMID: 21149228; PMCID: PMC3811929. 2. Rahmatinejad Z, Reihani H, Tohidinezhad F, Rahmatinejad F, Peyravi S, Pourmand A, Abu-Hanna A, Eslami S. Predictive performance of the SOFA and mSOFA scoring systems for predicting in-hospital mortality in the emergency department. Am J Emerg Med. 2019 Jul;37(7):1237-1241. doi: 10.1016/j.ajem.2018.09.011. Epub 2018 Sep 5. PMID: 30213476.

OBSERVATION.msofa.v0, EVALUATION.msofa_assessment.v0