T_MACS v.1

Troponin-only manchester acute coronary syndromes (T-MACS) decision aid is a prognostic tool in patients with chest pain that may be cardiac in nature.

Therese Lindberg

therese.lindberg@cambio.se

Cambio CDS

To calculate the risk of T-MACS.

Use to calculate the risk of T-MACS in order to rule out acute coronary syndrome. Formula: Probability of ACS (p) = 1/ (1+e^-(1.713E+0.847A+0.607R+1.417V+2.058S+1.208H+0.089T-4.766)) where: No Yes E: EKG ischemia 0 1 A: Worsening or crescendo angina 0 1 R: Pain radiation to the right arm or shoulder 0 1 V: Pain associated with vomiting 0 1 S: Sweating observed 0 1 H: Hypotension 0 1 T: hs-cTnT concentration on arrival hs-cTnT value Interpretation: Probability Risk Interpretation <0.02 Very low ACS ruled out. Consider discharge. ≥0.02 and <0.05 Low Consider serial troponin in ED ward, e.g. 3h troponin; consider discharge if normal. ≥0.05 and <0.95 Moderate Serial troponin in general ward and consider stress testing and/or CT coronary angiography thereafter. ≥0.95 High ACS ruled in. Refer to cardiology, treat for ACS.

1. Body R, Carlton E, Sperrin M, Lewis PS, Burrows G, Carley S, McDowell G, Buchan I, Greaves K, Mackway-Jones K. Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid: single biomarker re-derivation and external validation in three cohorts. Emerg Med J. 2017 Jun;34(6):349-356. doi: 10.1136/emermed-2016-205983. Epub 2016 Aug 26. PMID: 27565197; PMCID: PMC5502241.

OBSERVATION.t_macs.v0, EVALUATION.t_macs_assessment.v0