REACH_B_Score_guideline v.1
REACH-B score for hepatocellular carcinoma (HCC) estimates the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B.
To estimate the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B.
REACH-B score formula: Addition of the selected points: Variable & points: - Sex: Female=0, Male=2 - Age, years: 30–34=0, 35–39=1, 40–44=2, 45–49=3, 50–54=4, 55–59=5, 60–65=6 - ALT, U/L: <15=0, 15-44=1, >=45=2 - HBeAg: Negative=0, Positive=2 - Hepatitis B virus DNA level, copies/mL: <300 (undetectable)=0, 300–9,999=0, 10,000–99,999=3, 100,000–999,999=5, ≥106=4 Interpretation: HCC risk: REACH-B Score 3-year 5-year 10-year 0 0.0% 0.0% 0.0% 1 0.0% 0.0% 0.1% 2 0.0% 0.0% 0.1% 3 0.0% 0.1% 0.2% 4 0.0% 0.1% 0.3% 5 0.1% 0.2% 0.5% 6 0.1% 0.3% 0.7% 7 0.2% 0.5% 1.2% 8 0.3% 0.8% 2.0% 9 0.5% 1.2% 3.2% 10 0.9% 2.0% 5.2% 11 1.4% 3.3% 8.4% 12 2.3% 5.3% 13.4% 13 3.7% 8.5% 21.0% 14 6.0% 13.6% 32.0% 15 9.6% 21.3% 46.8% 16 15.2% 32.4% 64.4% 17 23.6% 47.4% 81.6%
1. Yang HI, Yuen MF, Chan HL, Han KH, Chen PJ, Kim DY, Ahn SH, Chen CJ, Wong VW, Seto WK; REACH-B Working Group. Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score. Lancet Oncol. 2011 Jun;12(6):568-74. doi: 10.1016/S1470-2045(11)70077-8. Epub 2011 Apr 14. PMID: 21497551.
OBSERVATION.reach_b.v0, EVALUATION.reach_b_assessment.v0
