Pediatric_SIRS_Sepsis_Septic_Shock_Criteria_guideline v.1

Temperature >38.5°C (101.3°F) or < 36°C (96.8°F)

Tachycardia or bradycardia (if <1 year)

Tachypnea or mechanical ventilation (related to an acute process)

Abnormal leukocyte count or >10% bands

Suspected or present source of infection

Cardiovascular dysfunction OR ARDS OR ≥ 2 other organ dysfunction

Cardiovascular dysfunction despite adequate fluid resuscitation

Age

Pediatric SIRS, Sepsis, and Septic Shock Criteria defines the severity of sepsis and septic shock for pediatric patients.

Maryam Razavi

maryam.razavi@cambio.se

@ Cambio CDS

To define the severity of sepsis and septic shock for pediatric patients.

Use in children <18 years old with ≥2 SIRS criteria should be screened for severe sepsis / septic shock. Formula: Selection series of Yes/No questions. Answer Yes assigned to 1 point and No assigned to 0. SIRS = ≥ 2 meets SIRS definition 1 of which must be abnormal temperature or leukocyte count. Sepsis = SIRS + Suspected infection Infectious etiology may be bacterial, viral, or fungal. Severe Sepsis = Sepsis + 1 of the following: Cardiovascular organ dysfunction Acute respiratory distress syndrome (ARDS) Evidence of ≥2 organ dysfunction (e.g., respiratory, renal, neurologic, hematologic, or hepatic) Septic Shock = Severe Sepsis + Cardiovascular Dysfunction (despite adequate fluid resuscitation)

Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005 Jan;6(1):2-8. doi: 10.1097/01.PCC.0000149131.72248.E6. PMID: 15636651.

OBSERVATION.pediatric_sirs_sepsis_septic_shock_criteria.v0, OBSERVATION.basic_demographic.v1

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