PLASMIC_Score_for_TTP v.1

PLASMIC Score for TTP predicts ADAMTS13 deficiency in suspected thrombotic thrombocytopenic purpura (TTP) with high discrimination.

Therese Lindberg

therese.lindberg@cambio.se

@CambioCDS

To predict ADAMTS13 deficiency in suspected thrombotic thrombocytopenic purpura (TTP) with high discrimination.

Use in hospitalized adult inpatients with suspected thrombotic thrombocytopenic purpura (TTP) who might benefit from early initiation of plasma exchange while awaiting ADAMTS-13 results. Interpretation: PLASMIC Score Risk group Risk of severe ADAMTS13 deficiency 0-4 Low 0% 5 Intermediate 6% 6-7 High 72%

Do not use in patients who have already undergone plasma exchange (i.e., intermediate and high risk groups, in whom therapeutic plasma exchange must be initiated immediately).

1. Bendapudi PK, Hurwitz S, Fry A, et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study. Lancet Haematol. 2017;4(4):e157-e164.

OBSERVATION.lab_test-full_blood_count.v1, OBSERVATION.lab_test_creatinine.v1, OBSERVATION.inr.v0, OBSERVATION.lab_test-bilirubin.v1, EVALUATION.plasmic_score_for_ttp.v0