Mekhail_Extension_of_the_Motzer_Score v.1

Mekhail Extension of the Motzer Score predicts metastatic renal cell carcinoma survival, more accurately than the Motzer Score.

Therese Lindberg

therese.lindberg@cambio.se

@CambioCDS

To predict metastatic renal cell carcinoma survival, more accurately than the Motzer Score.

Addition of selected points: 0 points 1 point Time from initial diagnosis to systemic treatment <1 year No Yes Prior treatment with radiation No Yes ≥2 sites of metastasis No Yes LDH >1.5× upper limit of normal (Normal: 140 U/L) No Yes Hgb <lower limit of normal (Normal: <12 g/dL (120 g/L)) No Yes Corrected serum calcium >10 mg/dL (3 mmol/L) No Yes Interpretation: Score Risk Median Survival 0-1 Favorable 28 months 2 Intermediate 14 months ≥3 Poor 5 month

1. Mekhail TM, Abou-jawde RM, Boumerhi G, et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma. J Clin Oncol. 2005;23(4):832-41.

OBSERVATION.lab_test-full_blood_count.v1, OBSERVATION.lab_test_serum_calcium.v1, EVALUATION.mekhail_extension_of_the_motzer_score_assessment.v0, OBSERVATION.mekhail_extension_of_the_motzer_score.v0, OBSERVATION.lab_test-ldh.v0