LM_Revised_eGFR v.0

Revised Lund-Malmö eGFR calculates the relative glomerular filtration rate (GFR) in adults ≥ 18 years and provides a superior estimate of the GFR compared with the MDRD, CKD-EPI and original LM equations. Input variables include gender, age (in years) and plasma creatinine value. GFR is calculated as ml/min/1.73m2.

Eneimi Allwell-Brown

models@cambiocds.com

© Cambio Healthcare Systems

Calculation of relative GFR using LM Revised equation.

To calculate the relative eGFR using the LM Revised equation: e^X−0.0158×age+0.438×ln(age) and; Female and pCr<150: X=2.50+0.0121×(150–pCr) Female and pCr≥150: X=2.50−0.926×ln(pCr/150) Male and pCr<180: X=2.56+0.00968×(180−pCr) Male and pCr≥180: X=2.56−0.926×ln(pCr/180) where; e = Euler's number (Napier's constant), ln = natural logarithm, pCr = plasma creatinine in umol/L, age = patient's age in years

Not for use in patients on dialysis or with traumatic spinal cord lesions, myelomeningocele or other disorders causing marked muscle wasting.

Nyman U, Grubb A, Larsson A, Hansson LO, Flodin M, Nordin G, Lindström V, Björk J. The revised Lund-Malmö GFR estimating equation outperforms MDRD and CKD-EPI across GFR, age and BMI intervals in a large Swedish population. Clinical Chemistry and Laboratory Medicine (CCLM). 2014 Jun 1;52(6):815-24.

OBSERVATION.lab_test-urea_and_electrolytes.v1, OBSERVATION.basic_demographic.v1, OBSERVATION.estimated_glomerular_filtration_rate.v1