Khorana_Risk_Score_Venous_Thromboembolism_Cancer_Patients v.0

Khorana Risk Score for Venous Thromboembolism in Cancer Patients predicts risk of VTE for cancer patients depending on type of cancer and other factors.

Therese Lindberg

therese.lindberg@cambio.se

@CambioCDS

To predict risk of VTE for cancer patients depending on type of cancer and other factors.

Khorana Risk Score is calculated based on 5 parameters: Cancer type, Pre-chemotherapy platelet count ≥350x10⁹/L, Hemoglobin level <10 g/dL or using RBC growth factors, Pre-chemotherapy leukocyte count >11x10⁹/L and BMI ≥35 kg/m². Use in general cancer patients (i.e., solid tumors and lymphomas). Score interpretation: Risk Group Score 2.5-month rate of VTE Low 0 0.3 - 0.8% Intermediate 1 - 2 1.8 - 2.0% High ≥3 6.7 - 7.1%

Do not use in patients with brain tumors or myelomas.

1. Khorana AA, et al. Development and validation of a predictive model for chemotherapy-associated thrombosis. Blood 2008;111:4902-7.

OBSERVATION.lab_test-full_blood_count.v1, EVALUATION.khorana_risk_score_venous_thromboembolism_cancer_patients.v0, OBSERVATION.body_mass_index.v2