IBI_risk_Febrile_Infants v.1
Step-by-step approach to febrile infants identifies febrile infants ≤90 days old at low risk of invasive bacterial infection (IBI).
To calculate the risk for invasive bacterial infection (IBI).
Use to identify febrile infants ≤90 days old at low risk of (and thus rule out) IBI. The assessment is based on a step-by-step approach where the individual variables are Yes or No. The formulas are as follows: Ill-appearing (Yes) = High risk Ill-appearing (No) + Age≤21 days (Yes) = High risk Ill-appearing (No) + Age≤21 days (No) + Leukocyturia (Yes) = High risk Ill-appearing (No) + Age≤21 days (No) + Leukocyturia (No) + Procalcitonin ≥0.5 (Yes) = High risk Ill-appearing (No) + Age≤21 days (No) + Leukocyturia (No) + Procalcitonin ≥0.5 ng/mL (No) + CRP >20 mg/L or ANC >10,000/mm^3 (Yes) = Intermediate risk Ill-appearing (No) + Age≤21 days (No) + Leukocyturia (No) + Procalcitonin ≥0.5 ng/mL (No) + CRP >20 mg/L or ANC >10,000/mm^3 (No) = Low risk Interpretation Risk group: IBI risk: Low 0.7% Intermediate 3.4% High 8.1%
Mintegi S, Bressan S, Gomez B, Da Dalt L, Blázquez D, Olaciregui I, de la Torre M, Palacios M, Berlese P, Benito J. Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection. Emerg Med J. 2014 Oct;31(e1):e19-24. doi: 10.1136/emermed-2013-202449. Epub 2013 Jul 14. PMID: 23851127.
OBSERVATION.ibi_risk_febrile_infants.v0, EVALUATION.ibi_risk_febrile_infants_assessment.v0
