Hypoglycemia_Risk_Score v.1

Hypoglycemia Risk Score predicts 12-month risk of hypoglycemic episodes in T2DM patients.

Therese Lindberg

therese.lindberg@acmbio.se

@CambioCDS

Predicts 12-month risk of hypoglycemic episodes in T2DM patients.

The risk score is calculated based on 6 parameters: History of ED or hospital admission due to hypoglycemia, Ed visits last 12 months, insulin use, sulfonylurea use, severe or end-stage kidney disease and age. Interpretation: Variables: Risk category: Risk of hypoglycemia admission in 12 months: ≥3 previous hypoglycemia admissions, OR High >5% 1-2 previous hypoglycemia admission(s) + insulin use 0 previous hypoglycemia admissions + no insulin use + no sulfonylurea use, OR Low <1% 0 previous hypoglycemia admissions + no insulin use + sulfonylurea use + age <77 years + no severe or end-stage kidney disease, OR 0 previous hypoglycemia admissions + insulin use + age <77 years + <2 ED visits All other risk factor combinations Intermediate 1-5%

1. Karter AJ, Warton EM, Lipska KJ, et al. Development and Validation of a Tool to Identify Patients With Type 2 Diabetes at High Risk of Hypoglycemia-Related Emergency Department or Hospital Use. JAMA Intern Med. 2017;177(10):1461-1470.

OBSERVATION.basic_demographic.v1, EVALUATION.hypoglycemia_risk_score.v0