HIV_Needle_Stick_Risk_Assessment_Stratification_Protocol_guideline v.1

HIV Needle Stick Risk Assessment Stratification Protocol (RASP) quantifies HIV exposure risk by source and exposure type and the need for prophylaxis.

Maryam Razavi

maryam.razavi2009@gmail.com

@CambioCDS

To help healthcare workers decide on the use of postexposure prophylaxis (PEP) for HIV exposure.

HIV Needle Stick Risk Assessment Stratification Protocol (RASP) variables and related values: - Source population (Acute AIDS illness defined as “end-stage AIDS, hospitalized, high viral load” Unknown HIV status, high-risk situation defined as “suspected HIV, IV drug user, an unknown needle with high local HIV prevalence”): Known HIV+: acute AIDS illness=1, Known HIV+: asymptomatic HIV=10, Unknown HIV status: high-risk situation=100, Unknown HIV status: low-risk situation=1000. - Inoculum type: Fresh blood=1, Other high-risk fluids (e.g., semen)=10, Dried old blood=100, Low-risk secretions (e.g., tears, urine, saliva)=1000. - Method of transmission: Intravenous=1, Deep intramuscular=10, Deep transcutaneous with visible bleeding=100, Superficial transcutaneous without bleeding=200, Mucosal contact only=500, Intact skin=1000. - Volume of inoculum: Massive (e.g., transfusion)=100, Measurable (>1 mL)=10, Moderate (large-bore, hollow needle >22 g)=5, Small (small-bore, hollow needle <22 g)=3, Trace surface only (e.g., suture needle). Formula: Basic risk = 1 / (Source population x Inoculum type x Method of transmission) Total risk = Basic risk x Volume of inoculum

1. Vertesi L. Risk Assessment Stratification Protocol (RASP) to help patients decide on the use of postexposure prophylaxis for HIV exposure. CJEM. 2003 Jan;5(1):46-8.

OBSERVATION.hiv_needle_stick_risk_assessment_stratification_protocol_rasp.v0