Gleason_score v.1

Provides prognostic information on prostate cancer based on microscopic tumor appearance.

Syeeda S Farruque

models@cambiocds.com

© Cambio Healthcare Systems

This tool helps to stage prostate cancer based on biopsy findings.

The Gleason Score is the standard staging criteria for prostate cancer. The score contains 3 sections which are primary, secondary and tertiary sections that relate to grades. Each grade is scored from 1 to 5 with a total score made up of summing the primary and secondary graded sections for a maximum score of 10 and a minimum of 2. The Tertiary or minor grade score is reported but doesn't affect the total score. Primary grade The dominant pattern of the tumor (>50% of total pattern seen) Secondary grade The highest grade pattern seen after the primary pattern Tertiary grade Small component of a third (generally more aggressive) pattern Grading System: Gleason Score Prognostic Grade Group Gleason score ≤ 6: I Gleason score 3 + 4 = 7: II Gleason score 4 + 3 = 7: III Gleason score 8: IV Gleason score 9-10: V

Do not use for diagnostic purposes without also considering other evidence.

Ref. 1: Pierorazio PM, Walsh PC, Partin AW, Epstein JI. Prognostic Gleason grade grouping: data based on the modified Gleason scoring system. BJU international. 2013;111(5):753-760. doi:10.1111/j.1464-410X.2012.11611.x. Ref 2: Cancercentrum. Nationellt vårdprogram - Prostatacancer. 2017-02-28. Available from: https://www.cancercentrum.se/samverkan/cancerdiagnoser/prostata/vardprogram/

OBSERVATION.gleason_score_for_prostate_cancer.v1, EVALUATION.gleason_assessment.v1