Glasgow_alcoholic_hepatitis_score v.1

The tool to assess the condition and predict the 28-day and 84-day survival rate outcomes in patients with alcoholic hepatitis.

Winner Ng

dokter.winner@gmail.com

@CambioCDS

To predict the 28-day and 84-day survival rate outcomes in patients with alcoholic hepatitis.

Glasgow Alcoholic score is calculated by the addition of the following points: - age : <50 yrs: 1p, ≥50 yrs: 2p - white blood cell counts: <15*10^9: 1p, ≥15*10^9: 2p - urea level: <5 mmol/L: 1p, ≥5 mmol/L: 2p - PT ratio: < 1.5: 1p, 1.5-2: 2p, >2: 3p - bilirubin: <125 μmol/L: 1p, 125-250 μmol/L: 2p, >250 μmol/L: 3p The Glasgow Alcoholic Hepatitis Score ranges from 5 to 12 as the minimum and maximum score, respectively. The assessment is to be performed on day 1 of admission and day 6-9. Scores of less than 9 show a much better 28- and 84-day survival than scores above 9 or above (87%/79% vs. 46%/40%). The score is less sensitive but more accurate than the Modified Discriminant Function or MELD scores.

Not to be used in other causes of hepatitis.

1. Forrest EH, Evans CD, Stewart S, Phillips M, Oo YH, McAvoy NC, Fisher NC, Singhal S, Brind A, Haydon G, O'Grady J, Day CP, Hayes PC, Murray LS, Morris AJ. Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Gut. 2005 Aug;54(8):1174-9. PubMed PMID: 16009691; PubMed Central PMCID: PMC1774903.

OBSERVATION.basic_demographic.v1, OBSERVATION.lab_test-full_blood_count.v1, OBSERVATION.lab_test-urea_and_electrolytes.v1, OBSERVATION.lab_test-liver_function.v1, OBSERVATION.lab_test-coagulation_profile.v1, OBSERVATION.glasgow_alcoholic_hepatitis_score.v0, EVALUATION.glasgow_alcoholic_hepatitis_score.v0