Diagnostic_Criteria_FH v.1

US (MEDPED) diagnostic criteria for Familial Hypercholesterolemia (FH) diagnoses familial hypercholesterolemia using age, family history, and total cholesterol (the MEDPED criteria).

Emma Malm

emma.snygg@hotmail.com

Cambio CDS

To diagnose familial hypercholesterolemia with the MEDPED criteria.

Use for patients with suspected familial hypercholesterolemia (FH), including those with elevated cholesterol and/or personal or family history of premature cardiac events. Instructions: 1. Select appropriate age 2. Select appropriate degree relative with FH 3. If patient's cholesterol is higher than cutoff, MEDPED criteria for FH are met Age (years) First Degree relative with FH Second Degree relative with FH Third Degree relative with FH <20 220 (mg/dL) 230 240 20-29 240 250 260 30-39 270 280 290 ≥40 290 300 310

1. Williams RR, Hunt SC, Schumacher MC, Hegele RA, Leppert MF, Ludwig EH, Hopkins PN. Diagnosing heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics. Am J Cardiol. 1993 Jul 15;72(2):171-6. doi: 10.1016/0002-9149(93)90155-6. PMID: 8328379.

OBSERVATION.diagnostic_criteria_fh.v0, EVALUATION.diagnostic_criteria_fh_assesment.v0, OBSERVATION.lab_test-lipids.v1