DASH_for_recurrent_VTE v.1

The DASH Prediction Score is an instrument for risk assessment of recurring venous thromboembolism (VTE) in patients with first time unprovoked VTE, and thereby aid in evaluating the need for continous anticoagulant therapy. For specific risk rates, please see the detailed description.

Dennis Forslund

models@cambiocds.com

Cambio Healthcare Systems

To assess the risk of recurring venous thromboembolism (VTE) in patients with first time unprovoked VTE, and thereby aid in evaluating the need for continous anticoagulant therapy.

Use to assess the risk of recurring venous thromboembolism (VTE) in patients with first time unprovoked VTE, and thereby aid in evaluating the need for continous anticoagulant therapy. The prediction guide is based on four parameters each contributing points to the total score; - D-dimer abnormal 2p - Age ≤ 50 years 1p - Male sex 1p - Hormone use at VTE onset -2p The maximum total score is 4p. The result is associated with an estimation of the annual risk of recurring VTE; -2p - 1,8 % -1p - 1 % 0p - 2,4 % 1p - 3,9 % 2p - 6,3 % 3p - 10,8 % 4p - 19,9 %

The prediction score is intended for patients with first time unprovoked VTE solely. The studies used to develope the score deliberately excluded all patients with known VTE factors (surgery, trauma, active cancer, immobility, pregnancy etc) save hormone therapy and oral contraception.

Tosetto A, Iorio A, Marcucci M, Baglin T, Cushman M, Eichinger S, Palareti G, Poli D, Tait RC, Douketis J. Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH).J Thromb Haemost. 2012 Jun;10(6):1019-25. Kearon C, Iorio A, Palareti G. Risk of recurrent venous thromboembolism after stopping treatment in cohort studies: recommendation for acceptable rates and standardized reporting. J Thromb Haemost. 2010;8:2313–2315

OBSERVATION.basic_demographic.v1, OBSERVATION.dash_for_recurrent_vte.v1, EVALUATION.dash_prediction_score_for_recurrent_vte_assessment.v1