Coronary_Perfusion_Pressure_guideline v.1

Determines the pressure gradient that drives coronary blood pressure, as the difference between DBP and left ventricular end-diastolic pressure.

Maryam Razavi

maryam.razavi@cambio.se

© Cambio CDS

To determine the pressure gradient that drives coronary blood pressure, as the difference between DBP and left ventricular end-diastolic pressure.

Variables: Diastolic Blood Pressure (DBP) mmHg, Pulmonary Capillary Wedge Pressure (PCWP) mmHg. Coronary Perfusion Pressure (CPP) = Diastolic Blood Pressure (DBP) - Pulmonary Capillary Wedge Pressure (PCWP)

Sutton RM, Friess SH, Maltese MR, Naim MY, Bratinov G, Weiland TR, Garuccio M, Bhalala U, Nadkarni VM, Becker LB, Berg RA. Hemodynamic-directed cardiopulmonary resuscitation during in-hospital cardiac arrest. Resuscitation. 2014 Aug;85(8):983-6. doi: 10.1016/j.resuscitation.2014.04.015. Epub 2014 Apr 28. PMID: 24783998; PMCID: PMC4087068. Heward SJ, Widrich J. Coronary Perfusion Pressure. [Updated 2021 May 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551531/ Duncker DJ, Bache RJ. Regulation of coronary blood flow during exercise. Physiol Rev. 2008 Jul;88(3):1009-86. doi: 10.1152/physrev.00045.2006. PMID: 18626066. Goodwill AG, Dick GM, Kiel AM, Tune JD. Regulation of Coronary Blood Flow. Compr Physiol. 2017 Mar 16;7(2):321-382. doi: 10.1002/cphy.c160016. PMID: 28333376; PMCID: PMC5966026.

OBSERVATION.blood_pressure.v2, OBSERVATION.pulmonary_capillary_wedge_pressure_pcwp.v0, OBSERVATION.coronary_perfusion_pressure_cpp.v0