Benzodiazepine_Conversion_Calculator v.1

Provides equivalents between different benzodiazepines.

Henrik Honkanen

henrik.honkanen@stud.ki.se

@Cambio CDS

Provides equivalents between different benzodiazepines.

Intended for use when interchanging benzodiazepines. This calculator should be used as a reference for oral benzodiazepine conversions. Equipotent benzodiazepine doses are reported as ranges due to paucity of literature supporting exact conversions, thus reported ranges are based on expert opinion and clinical experience published in psychiatric literature. Durations of action: -Very short acting: <6 hours -Short acting: 6-12 hours (ALPRAZolam, oxazepam, triazolam) -Intermediate acting: 12-24 hours (LORazepam, temazepam) -Long acting: >24 hours (chlordiazePOXIDE, diazePAM, clonazePAM)

Do not use to calculate the initial dose for a benzodiazepine naive patient.

1. Ashton CH. Benzodiazepines: How they work and how to withdraw. The Ashton Manual, Aug. 2002 Aug. 2. Silk KR, Tyrer P. Cambridge textbook of effective treatments in psychiatry. Cambridge University Press; 2008. 3. Saunders JB, Conigrave KM, Latt NC, Nutt DJ, Marshall EJ, Ling W, Higuchi S, editors. Addiction medicine. Oxford University Press; 2016 Aug 11. 4. Labbate LA, Fava M, Rosenbaum JF, Arana GW. Drugs for the treatment of depression. Handbook of Psychiatric Drug Therapy, 6th ed, Lippincott Williams & Wilkins, Philadelphia, PA. 2010:54. 5. Procyshyn RM, Bezchlibnyk-Butler KZ, Jeffries JJ, editors. Clinical handbook of psychotropic drugs. Hogrefe Verlag; 2019 May 15.

OBSERVATION.benzodiazepine_conversion_calculator.v0