BODE_Index_COPD_survival v.1

The tool to predict the 4-year survival rate in COPD patients.

Winner Ng

dokter.winner@gmail.com

@CambioCDS

To provide the 4-year-survival prediction for COPD patients. The tool serves as a supplementary material when discussing with patients regarding their prognosis based on a realistic and evidence-based source.

To be used on patients with COPD, defined as >20 pack-year smoking history and FEV1/FVC ratio <0.7, measured 20 mins after albuterol given. The BODE Index is calculated from four factors: - Percentage value of predicted FEV1 - Result of 6 Minute Walk Distance - mMRC Dyspnea Scale - Body Mass Index (BMI). The BODE Index will then be translated to a certain 4-year survival rate: - index of 0-2 will have a 80% of 4-year survival rate - index of 3-4 will have a 67% of 4-year survival rate - index of 5-6 will have a 57% of 4-year survival rate - index of 7-10 will have a 18% of 4-year survival rate

The tool is not to be used as to predict clinical response to therapy nor as a therapy guidance. Do not use in the presence of these conditions: - During acute exacerbations of COPD. - Asthma diagnosis. - Inability to perform bronchodilator test or 6 Minute Walk Test. - Myocardial infarct within four months. - Unstable angina. - CHF (NYHA class III or IV). - Likely to die within 3 years from a cause other than COPD.

1. Celli BR. The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease. New England Journal of Medicine. 2004; 350:10;1005-1012 doi:10.1056/NEJMoa021322. 2. Marin JM, Carrizo SJ, Casanova C, et al. Prediction of risk of COPD exacerbations by the BODE index. Respir Med. 2009;103(3):373-8.

EVALUATION.bode_index_for_copd_survival.v0, OBSERVATION.body_weight.v2, OBSERVATION.height.v2, OBSERVATION.body_mass_index.v2